Showing posts with label Harvard School of Public Health. Show all posts
Showing posts with label Harvard School of Public Health. Show all posts

Monday, December 19, 2011

Havard unveils findings on canned soup diet

Now this is something that has to be checked on your diet... eat in moderation...
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Posted: 23 November 2011


Test tube with samples
WASHINGTON: People who ate canned soup for five days straight saw their urinary levels of the chemical bisphenol A spike 1,200 percent compared to those who ate fresh soup, US researchers said on Tuesday.

The randomised study, described as "one of the first to quantify BPA levels in humans after ingestion of canned foods," was done by Harvard University researchers and appears in the Journal of the American Medical Association's November 23 issue.

"We've known for a while that drinking beverages that have been stored in certain hard plastics can increase the amount of BPA in your body," said lead author Jenny Carwile, a doctoral student in the Department of Epidemiology at Harvard School of Public Health.

"This study suggests that canned foods may be an even greater concern, especially given their wide use."

The chemical BPA is an endocrine disruptor that has been shown to interfere with reproductive development in animal studies at levels of 50 micrograms per kilogram of body weight and higher, though it remains uncertain if the same effects cross over to humans, according to the Environmental Protection Agency.

This study did not measure BPA levels by micrograms per kilogram of body weight, but rather by micrograms per litre of urine, so a direct comparison to the EPA-cited danger level in animals was not possible.

However, previous studies have linked BPA at lower levels than those found in the Harvard study to cardiovascular disease, diabetes and obesity in humans, Carwile told AFP in an email.

BPA is found in the lining of canned foods, cash register receipts, dental fillings, some plastics and polycarbonate bottles marked with the number 7.

Seventy-five people took part in the study, eating a 12-ounce serving of either fresh or canned soup for five days in a row. They were advised not to otherwise alter their regular eating habits.

After a two-day break, the groups switched and ate the opposite type of canned soup.

A urine analysis showed the canned soup eaters had 1,221 percent higher levels of BPA than those who ate the fresh soup.

BPA is typically eliminated in the urine and so any spike is usually considered temporary. The researchers did not measure how long elevated BPA stayed in the body, saying more study would be needed to examine that question.

The US government's health and environmental agencies are considering whether "further action is needed to address human health risks resulting from non-food-packaging uses of BPA," according to the EPA.

France's Agency for Food Health Safety (Anses) in September called for tougher preventive measures, warning that even "low doses" of the chemical had had a "confirmed" effect on lab animals and a "suspected" effect on humans.

Preventing exposure to BPA among infants, pregnant or nursing women was a "priority goal," Anses said.

Meanwhile, the Harvard study authors said their findings should encourage people who eat a lot of canned foods to opt for fresh instead, and should serve as a red flag to manufacturers who use BPA to make cans.

"The magnitude of the rise in urinary BPA we observed after just one serving of soup was unexpected and may be of concern among individuals who regularly consume foods from cans or drink several canned beverages daily," said senior author Karin Michels.

"It may be advisable for manufacturers to consider eliminating BPA from can linings."

- AFP/wk



Taken from ChannelNewsAsia.com; source article is below:
Havard unveils findings on canned soup diet


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Thursday, November 24, 2011

Vitamin D activates immune response to TB

Posted: 13 October 2011

Oily fish such as salmon are rich in Vitamin D
WASHINGTON: Vitamin D is needed to activate the immune system's response to tuberculosis, said a US study on Wednesday that could lead to new treatments for the lung disease that kills 1.8 million people per year.

Researchers have long known that vitamin D plays a role in the body's response to TB, but the study in the journal Science Translational Medicine shows it must be present in adequate levels to trigger the immune response.

This finding could be crucial to efforts to treat the disease in parts of the world like Africa, because people with dark skin tend to be more susceptible to TB and also are more likely to have vitamin D deficiencies.

Even though people can get vitamin D through sun exposure, dark skin contains more melanin which shields the body from ultraviolet rays and also reduces vitamin D production.

"Over the centuries, vitamin D has intrinsically been used to treat tuberculosis," said first study author Mario Fabri, who did the research for the study while at the University of California Los Angeles and is currently at the Department of Dermatology at the University of Cologne, Germany.

"Sanatoriums dedicated to tuberculosis patients were traditionally placed in sunny locations that seemed to help patients -- but no one knew why this worked," he said.

"Our findings suggest that increasing vitamin D levels through supplementation may improve the immune response to infections such as tuberculosis."

Previous studies by the same research team found that vitamin D played a key role producing a molecule called cathelicidin, which helps the innate immune system kill the tuberculosis bacteria.

The current findings show that vitamin D is necessary for the T-cells, which respond to threats as part of the body's adaptive immune system, to produce a protein called interferon which directs cells to attack the bacteria.

"At a time when drug-resistant forms of tuberculosis are emerging, understanding how to enhance natural innate and acquired immunity through vitamin D may be very helpful," said co-author Barry Bloom, former dean of the faculty at the Harvard School of Public Health.

The World Health Organization reported this week that 8.8 million people had TB last year, with about one quarter of those cases occurring in Africa and 40 percent in India and China.

-AFP/vl



Taken from ChannelNewsAsia.com; source article is below:
Vitamin D activates immune response to TB

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